Glycoconjugates are carbohydrates produced by covalently linking glycans with other molecules, such as proteins (glycopeptides and glycoproteins), lipids (glycolipids and lipopolysaccharides), amino acids (peptidoglycans), and other small molecule (glycosides), etc. Moreover, we also provide Custom Glycoconjugate Synthesis services for clients to help them develop the custom glycoconjugate structure.
Synthetic glycoconjugates serve as excellent tools for elucidating the role of natural glycoconjugates in various biological processes. It is crucial to actively develop chemical methods for conjugating carbohydrates with biomolecules. CD BioGlyco offers a range of glycoconjugate products to support research in this area.
CD BioGlyco provides glycopeptide products and ensures that our customers receive high-quality service in the rapidly advancing field of glycoprotein analysis, such as studies related to cancer biomarkers. glycopeptides are powerful chemical biology tools for exploring the complex functions of glycoproteins in biological processes such as cellular communication/jamming, immune response, and disease etiology. They have a vast swath of applications in many aspects of research spanning from structural biology, to drug discovery and biomarker identification. All of our glycopeptides are expertly synthesized from start to finish and characterized for the highest quality.
| Cat. No. | Product Name |
| X23-03-YW112 | Sialylglycopeptide |
| X23-03-YW113 | A2G2-Peptide |
| X23-03-YW114 | A2-Peptide |
| X23-03-YW115 | A2[3]G2S1-Peptide |
| X23-03-YW116 | A2[6]G2S1-Peptide |
| X23-03-YW117 | A2[6]G1-Peptide |
| X23-03-YW118 | A2[3]G1-Peptide |
| X23-03-YW119 | SGN |
| X23-03-YW120 | A2[3]G2S1-Asn |
| X23-03-YW121 | A2G2-Asn |
| X23-03-YW122 | Neu5Gcα(2-6)-N-glycaN-Asn |
| X23-03-YW123 | A2-Asn |
| X23-03-YW124 | M3-Asn |
CD BioGlyco offers a diverse range of high-quality glycoamino acids products tailored to meet the demands of cutting-edge research in glycobiology and related fields. These glycoamino acids serve as indispensable building blocks for the synthesis of complex glycopeptides, glycoproteins, and other glycoconjugates. Their versatility and reliability make them essential tools for studying various biological processes. Our glycoamino acids are meticulously synthesized and subjected to stringent quality control measures to ensure exceptional purity, stability, and reliability in your experiments. Please click the "Glycoamino Acids" button above to go through all of our glycoamino acid products.
These products are derivatized serine and threonine residues with various glycan structures, facilitating the study of glycoprotein structures and functions.
| Cat. No. | Product Name |
| X22-07-ZQ387 | Fmoc-L-Ser (α-D-GalNAc(Ac)3)-OH |
| X22-07-ZQ392 | Fmoc-L-Ser (α-D-ManNAc(Ac)3)-OH |
| X22-07-ZQ394 | Fmoc-L-Ser(β-D-Gal(Ac)4)-OH |
| X22-07-ZQ404 | Fmoc-L-Thr (α-D-GalNAc(Ac)3)-OH |
| X22-07-ZQ410 | Fmoc-L-Thr (β-D-Gal(Ac)4)-OH |
These compounds feature glycosylated asparagine residues and are crucial for understanding protein glycosylation patterns.
| Cat. No. | Product Name |
| X22-07-ZQ384 | Fmoc-L-Asn (β-D-GlcNAc(Ac)3)-OH |
| X22-07-ZQ386 | Fmoc-L-Asn(GlcNAcβ(1-4)GlcNAc)-OH |
This category comprises amino acids modified with complex glycan moieties, enabling the study of intricate glycan-protein interactions.
| Cat. No. | Product Name |
| X22-07-ZQ400 | Fmoc-L-Ser (Galβ(1-3)GalNAc)-OH |
| X22-07-ZQ417 | Fmoc-L-Thr (β-D-Lac(Ac)7)-OH |
These amino acids are synthesized from deoxyfructose and find applications in glycobiology and glycochemistry studies.
| Cat. No. | Product Name |
| X22-07-ZQ419 | N-(1-Deoxy-D-fructos-1-yl)-glycine |
| X22-07-ZQ420 | N-(1-Deoxy-D-fructos-1-yl)-β-alanine |
These Fmoc-protected amino acids contain specialized glycan linkages suitable for glycoprotein synthesis and glycan-protein interaction studies.
| Cat. No. | Product Name |
| X23-11-ZQ089 | Fmoc-Ser((Ac4Galβ(1-3))Me,Ac4Neu5Acα(2-6)AcGalNAcα)-OH |
| X23-11-ZQ092 | Fmoc-Thr((Ac4Galβ(1-3))Me,Ac4Neu5Acα(2-6)AcGalNAcα)-OH |
At CD BioGlyco, our lipopolysaccharide products encompass a variety of glycolipids, each offering distinct applications in research and medical fields. Please click the "Lipopolysaccharides" button above to go through all of our lipopolysaccharide products.
These products are derived from various bacterial strains and are used in immunological and microbiological research.
These products have been modified or treated for specific research or application purposes.
| Cat. No. | Product Name |
| XGB679 | Lipopolysaccharides from Escherichia coli O111:B4, Detoxified |
| XGB695 | Lipopolysaccharides from Escherichia coli O26:B6, Ready made solution, 1 mg/mL, 0.2 μm filtered |
These products undergo different extraction and preparation processes for laboratory applications and biomedical research.
| Cat. No. | Product Name |
| XGB697 | Lipopolysaccharides from Proteus mirabilis |
| XGB715 | Lipopolysaccharides from Salmonella typhosa, purified by gel-filtration chromatography |
| XGB717 | Lipopolysaccharides from Serratia marcescens |
Sphingolipids are a class of lipids with critical roles in cell structure, signaling, and regulation. CD BioGlyco offers a diverse range of sphingolipid products that are invaluable for research in various fields including cell biology, immunology, and neuroscience. Please click the "Sphingolipids" button above to go through all of our sphingolipid products.
Neutral glycosphingolipids are a subgroup of glycosphingolipids that lack a net charge at physiological pH due to the absence of sialic acid or sulfate residues in their carbohydrate moiety. They are characterized by a ceramide backbone linked to a neutral sugar head group. Neutral glycosphingolipids play important roles in various cellular processes including cell-cell recognition, cell adhesion, and membrane organization.
| Cat. No. | Product Name |
| XGB725 | N-(NBD-Aminocaproyl)sphingosine β-D-galactosyl |
| XGB726 | N-(NBD-Aminocaproyl)sphingosine β-D-lactosyl |
| XGB727 | N-(NBD-Aminolauroyl)sphingomyelin |
| XGB728 | N-(NBD-Aminolauroyl)sphingosine β-D-lactosyl |
Sphingoid bases, also known as long-chain sphingoid bases or sphingoid long-chain bases (LCBs), are fundamental components of sphingolipids, a class of lipids found in cell membranes. They serve as the backbone for the synthesis of more complex sphingolipids, including ceramides, sphingomyelins, and glycosphingolipids.
| Cat. No. | Product Name |
| X23-11-ZQ096 | Sphingosine (d20:1) |
| X23-11-ZQ097 | Sphingosine (d16:1) |
| X23-11-ZQ098 | Sphingosine (d14:1) |
| XGB731 | D-erythro-Dihydrosphingosine 1-phosphate |
| XGB732 | Sphingosine 1-phosphate |
| XGB733 | D-Sphingosine |
| XGB734 | D-erythro-Dihydrosphingosine |
| XGB735 | D-threo-Dihydrosphingosine |
| XGB736 | DL-Dihydrosphingosine |
| XGB737 | L-threo-Dihydrosphingosine |
These are a subclass of sphingolipids that contain a phosphate group. They are involved in cell signaling, membrane structure, and cellular recognition processes.
| Cat. No. | Product Name |
| XGB730 | Ceramide phosphorylethanolamine |
| XGB738 | Sphingomyelin, ≥95% |
| XGB739 | Sphingomyelin, ≥98.0% (TLC) |
| XGB740 | Sphingosylphosphorylcholine |
Ceramides are a class of lipid molecules composed of sphingosine and a fatty acid. They are fundamental components of cell membranes and are involved in various cellular processes, including cell signaling, cell recognition, and apoptosis (programmed cell death)
| Cat. No. | Product Name |
| XGB741 | D-erythro-Ceramine C8 |
| XGB742 | Ceramide from bovine spinal cord |
| XGB743 | N-Acetyl-D-sphingosine |
| XGB744 | N-Hexanoyl-D-sphingosine |
| XGB745 | N-Octanoyl-D-sphingosine |
| XGB746 | Non-hydroxy fatty acid ceramide from bovine brain |
| XGB747 | Dihydroceramide C2 |
| XGB748 | Dihydroceramide C6 |
| XGB749 | Dihydroceramide C8 |
| XGB750 | N-Stearoyl-phytosphingosine |
| XGB751 | Phytoceramide C2 |
| XGB752 | D-erythro-Ceramide C8 1-phosphate |
| XGB753 | Ceramide 1-phosphate from bovine brain |
These glycosphingolipids serve as essential tools in various fields of research, including neuroscience, immunology, and cancer biology, facilitating the study of cellular processes and disease mechanisms. You can click the "Acidic glycosphingolipids" button to explore our all acidic glycosphingolipid products.
Besides, CD BioGlyco also offers a vast array of other glycolipid products, here totaling more than 500 other glycolipid items. Glycolipids play crucial roles in various biological processes, including cell-cell recognition, cell signaling, and membrane stability. They are involved in numerous physiological and pathological phenomena, making them essential for both basic research and therapeutic development. You can click the "Other Glycolipids" button to explore our all other glycolipids.
These glycosphingolipids serve as crucial components in cell signaling, recognition, and differentiation processes. They are vital for cell-cell interactions and can be utilized in studies related to cell surface markers and glycosylation patterns. (GlcSph, Lacsph, Lc3sph, Lc4sph, nLc4sph, Sialyl-Lc4sph, H Antigen sph, A Antigen sph, B Antigen sph, SSEA-4 sph, GB3sph, GB4sph, GB5sph, Globo H sph, iGB3sph, iGB4sph, iGB5sph, iGlobo H sph, more product)
| Cat. No. | Product Name |
| X23-11-ZQ099 | Glcsph (d18:1) |
| X23-11-ZQ117 | Lacsph (d20:1) |
| X23-11-ZQ129 | Lc3sph (d18:1) |
| X23-11-ZQ143 | Lc4sph (d18:1) |
| X23-11-ZQ283 | GB3sph (d18:1) |
These ceramides play roles in cell adhesion, migration, and immune response modulation. They are significant in membrane structure and function and can be utilized in research on lipid metabolism and glycosphingolipid-related diseases. (GlcCer, GalCer, LacCer, Lc3Cer, Lc4Cer, Sialyl-Lc4Cer, Lewis a Cer, nLc4Cer, Sialyl-nLc4Cer, Lewis x Cer, GB3Cer, GB4Cer, GB5Cer, Globo H Cer, iGB3Cer, iGB4Cer, iGB5Cer, iGlobo H Cer, more product)
| Cat. No. | Product Name |
| X23-11-ZQ101 | GlcCer (d18:1/8:0) |
| X23-11-ZQ112 | GalCer (d18:1/16:0) |
| X23-11-ZQ118 | LacCer (d18:1/8:0) |
| X23-11-ZQ131 | Lc3Cer (d18:1/8:0) |
| X23-11-ZQ145 | Lc4Cer (d18:1/8:0) |
These glycolipids are crucial in cell adhesion, signaling, and immune response regulation. They are relevant in cancer biology, inflammation, and various pathological processes involving sialylation. (Sialyl-Lc4sph, Sialyl-Lc4Cer, Sialyl-Lewis x sph, Sialyl-Lewis x Cer, Sialyl-iGB5sph, Sialyl-iGB5Cer, more products)
| Cat. No. | Product Name |
| X23-11-ZQ158 | Sialyl-Lc4sph (d20:1) |
| X23-11-ZQ164 | Sialyl-Lc4Cer (d18:1/24:1) |
| X23-11-ZQ255 | Sialyl-Lewis x sph (d18:1) |
| X23-11-ZQ261 | Sialyl-Lewis x Cer (d18:1/20:0) |
| X23-11-ZQ409 | Sialyl-iGB5sph (d18:1) |
These glycolipids are essential in blood group antigenicity, immune recognition, and host-pathogen interactions. They are significant in understanding immunology, transfusion medicine, and disease diagnostics. (Lewis a sph, Lewis a Cer, H Antigen sph, H Antigen Cer, A Antigen sph, A Antigen Cer, B Antigen sph, B Antigen Cer, more products…)
| Cat. No. | Product Name |
| X23-11-ZQ171 | Lewis a sph (d18:1) |
| X23-11-ZQ173 | Lewis a Cer (d18:1/8:0) |
| X23-11-ZQ215 | H Antigen Cer (d18:1/8:0) |
| X23-11-ZQ227 | A Antigen sph (d18:1) |
| X23-11-ZQ241 | B Antigen sph (d18:1) |
These glycolipids are markers for pluripotent stem cells and embryonic development. They play crucial roles in cell fate determination and can be used in stem cell research and regenerative medicine. (SSEA-4 sph, SSEA-4, more products)
| Cat. No. | Product Name |
| X23-11-ZQ339 | SSEA-4 sph (d18:1) |
| X23-11-ZQ341 | SSEA-4 (d18:1/8:0) |
DOI: 10.4172/2157-2526.1000150
Technology: Lectin, Glycan microarrays, Isothermal titration calorimetry (ITC), High-throughput screening (HTS), Surface plasmon resonance (SPR), Fluorescence polarization (FP), Weak affinity chromatography (WAC)
Journal: Journal of Bioterrorism & Biodefense
Published: 2016
Results: This paper focuses on the use of glycobiology in anti-adhesion strategies against biological threat agents, focusing on the mechanisms of how pathogens attach and invade host cells through carbohydrate-lectin interactions. It is shown that glycoconjugates and glycomimetics can be used to interfere with the pathogen attachment process, thereby preventing and controlling infection. The paper details the interactions of glycoconjugates of several pathogens (e.g., Escherichia coli, Shiga toxin, cholera toxin, botulinum toxin, Ebola virus, and Zika virus) with host cell receptors and demonstrates the potential of using multivalent glycoconjugates to block these interactions.
Fig.1 Examples of multivalent glycoconjugates inhibiting microbial binding. (Utratna, et al., 2016)
How do glycoconjugates improve the efficacy of vaccines?
When the antigen is attached to a glycan, the immune system perceives and reacts more strongly towards it in counterpoint with free antigens, implying enhanced protection. It is particularly important in the production of vaccines against bacterial pathogens, as this glycan acts like a polysaccharide capsule from the bacteria and activates an immune response.
How are glycoconjugates utilized in research to study glycan-protein interactions?
Knows the mechanisms of cell-cell communication and relationships through glycan-binding proteins Here, we examine the ways in which pathogens use glycan interactions for host-cell entry and consider how this information can be applied to treat infectious diseases by targeting bacterial adhesion.
At CD BioGlyco, our glycoconjugate products offer significant potential in biomedical research, providing powerful tools for the prevention, diagnosis, and treatment of various diseases. Please feel free to contact us to get the quote according to your needs!
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