Silver Glyconanoparticle Production Service

Overview of Silver Glyconanoparticles

Silver glyconanoparticles refer to a class of nanomaterials where sugar moieties or saccharide molecules are attached to the surface of silver nanoparticles. Glycosylated silver nanoparticles retain the physical and chemical properties of silver nanoparticles and impart unique biological functions, especially the ability of the sugar molecules to interact with sugar receptors, lectins, and other glycan-binding proteins in the body. These characteristics enable silver glyconanoparticles to have wide applications in various fields, including biomedical research, drug delivery, sensors, and antimicrobial activities.

The silver glyconanoparticle production service at CD BioGlyco provides products for silver nanoparticles functionalized with various glycosyl groups. Silver glyconanoparticles, functionalized with specific sugars, combine the inherent antimicrobial properties of silver nanoparticles with the biological recognition capabilities of glycan groups.

CD BioGlyco offers comprehensive solutions for producing silver glyconanoparticles based on our GlycoNano™ Platform, utilizing Advanced Techniques for Glyconanoparticles to address a wide range of research and industrial demands for Glyconanoparticle Development. we combine the distinct properties of silver nanoparticles with the functional versatility of glycosyl groups, enabling precise and efficient synthesis.

Chemical reduction method Sol-gel method Biosynthesis method Electrochemical method	This technique utilizes reducing agents to transform silver ions into silver nanoparticles. During the reduction process, glycan molecules are chemically attached to the surface of the nanoparticles.
	Silver nanoparticles are synthesized via sol-gel reactions, and glycan moieties are grafted onto their surfaces through either chemical bonding or physical adsorption, ensuring strong and durable glycan functionalization.
	Harnessing the natural capabilities of microorganisms or plant extracts, this environmentally friendly approach produces silver nanoparticles.
	Through electrochemical processes, silver nanoparticles are deposited on silver electrodes, and glycan molecules are adsorbed onto their surfaces via electrostatic interactions.

With our equipment and facilities, our service provides precise and scalable production from milligrams to grams.

Chitosan-Silver Nanoparticle Production Service

Glucosamine-Silver Nanoparticle Production Service

Exopolysaccharide-Silver Nanoparticle Production Service

Galactose-Silver Nanoparticle Production Service

Mannose-Silver Nanoparticle Production Service

Glucose-Silver Nanoparticle Production Service

Cyclodextrin-Silver Nanoparticle Production Service

Glyconanoparticle Characterization Service for Silver Glyconanoparticles

Some analytical methods for silver glyconanoparticles. (CD BioGlyco)

Applications

Glycan molecules can specifically bind to glycan receptors on cell surfaces. This allows silver glyconanoparticles to target specific cells or tissues, improving drug delivery efficiency and reducing side effects.
Silver nanoparticles are naturally antimicrobial. Adding glycan groups improves their biocompatibility, reduces toxicity to normal cells, and enhances their ability to inhibit bacteria, fungi, and viruses.
Silver glyconanoparticles can act as recognition elements in sensors. They interact with glycan molecules or glycan-binding proteins, making them useful for disease detection and environmental monitoring.

Advantages

Glycan groups enable specific interactions with glycan receptors or glycan-binding proteins, allowing precise targeting of cells or tissues.
Glycan molecules enhance the biocompatibility of silver nanoparticles, reducing toxicity and increasing stability and circulation time in the body.
Glycan modification not only improves compatibility but also strengthens antibacterial and antiviral effects.
Silver glyconanoparticles combine the antimicrobial and catalytic properties of silver nanoparticles with specific interactions provided by glycan groups, expanding their applications.

Frequently Asked Questions

What production scales are supported for silver glyconanoparticle production?
Our silver glyconanoparticle production service is equipped to support a wide range of scales, from milligrams to grams. This scalability allows us to meet both research-focused small-scale needs and industrial production demands.
What technologies are used in the production of silver glyconanoparticles?
Our production process uses advanced techniques such as chemical reduction, sol-gel synthesis, biosynthesis, and electrochemical methods. These technologies ensure the precise functionalization of nanoparticles with glycosyl groups, achieving high stability, scalability, and biocompatibility.

Publication

Technology: Dynamic light scattering, Transmission electron microscopy, Fluorescence resonance energy transfer, Surface-enhanced Raman spectroscopy, Colorimetric assays, MALDI-TOF mass spectrometry

Journal: Frontiers in Chemistry

IF: 3.5

Published: 2021

Results: This study highlights recent advancements in using silver glyconanoparticles and related nanomaterials, such as gold nanoparticles (AuNPs) and quantum dots (QDs), for detecting lectins, viruses, bacteria, and cancer cells. The research focuses on the functionalization of nanoparticles with carbohydrate groups to enhance their biological recognition and diagnostic potential. These glyconanoparticles exhibit high specificity and sensitivity in detecting pathogens, diagnosing diseases, and imaging cancer cells, underscoring their growing role in biomedicine.

Table 1. GlycoNPs and QDs for detection, diagnosis, and imaging, indexed by particle type. (Hernando, et al., 2021)

Table 1. GlycoNPs and QDs.

At CD BioGlyco, we offer the silver glyconanoparticle production service that delivers high-quality glycosylated silver nanoparticles to support a wide range of research and industrial applications. Contact us today to discover how our services can drive your research forward.

Reference

From Wikipedia: https://en.wikipedia.org/wiki/Chitosan#
From Wikipedia: https://en.wikipedia.org/wiki/Glucosamine#
From Wikipedia: https://en.wikipedia.org/wiki/Cyclodextrin#
Tukenmez, U.; et al. The relationship between the structural characteristics of lactobacilli-EPS and its ability to induce apoptosis in colon cancer cells in vitro. Scientific reports. 2019, 9(1): 8268.
Hernando, P.J.; et al. Recent developments in the use of glyconanoparticles and related quantum dots for the detection of lectins, viruses, bacteria and cancer cells. Frontiers in Chemistry. 2021, 9: 668509.

This service is for Research Use Only, not intended for any clinical use.