Characterization of Uracil Nucleotide Derivatives

Uridine nucleotide, as a basic nucleotide, plays an important regulatory role in metabolism. According to research, its derivatives also have important functions. Clinical studies have shown that uracil derivatives can participate in the synthesis of the detoxifying substance glucuronic anhydride, which can be used to treat hepatitis and improve coronary heart disease, rheumatoid arthritis, and other symptoms. Uridine nucleotide derivatives are the most important antiviral and antitumor drugs currently used by humans. They play an irreplaceable role in the treatment of hepatitis B and leukemia, the inhibition of tumor cell growth, and the production of antiviral drugs.

Uracil Nucleotide Derivative Production Service at CD BioGlyco

For the production of uracil nucleotide derivatives, CD BioGlyco offers a variety of methods for client choice.

• Chemical Method
  This method utilizes a phosphorylation reaction to change the functional groups of the raw material by increasing or decreasing them to obtain the target compound.
• Biological method
  This method specifically contains several main categories:
  • Enzyme-catalyzed
  • Enzymatic
  • Microbial fermentation

Meanwhile, the biological method is easy to operate, in mild conditions, and environmentally friendly. We provide suitable production solutions according to client's needs and will continue to optimize our production solutions.

In summary, we manufacture uracil nucleotide derivatives including, but not limited to, 5-fluorouracil nucleotides, which can affect DNA synthesis, aglycone uracil nucleotide, which is used in the treatment of leukemia, and the antiviral drug, fluoride aglycone uracil nucleotide (FIAu), among others.

Fig.1 Production of uracil nucleotide derivatives. (CD BioGlyco)

Applications

• In drug discovery, uracil nucleotide derivatives can be used in research for the production of antitumor drugs.
• In the field of food processing, uracil nucleotide derivatives can be used in research for the production of spices.
• In the field of agriculture, uracil nucleotide derivatives can be used in the research of plant growth promoters.

Advantages

• We offer several routes for the production of uracil nucleotide derivatives, which helps our clients carry out their research efficiently.
• Uridine nucleotide derivatives have a good effect in anti-virus as well as anti-tumor, so its production helps to study the mechanism of virus-aligned tumor production.
• We have a professional uracil nucleotide derivatives research team to provide accurate and professional guidance to our clients.

CD BioGlyco has many years of experience in researching Nucleotides and Derivatives of Nucleotides. With a professional research team and first-class laboratory equipment, we have been providing uracil nucleotide derivatives production services to clients all over the world. If you are interested in our services, please do not hesitate to contact us.