Nucleotide Derivative Production Service

The Significance of Nucleotide Derivatives

Nucleotide Derivatives are chemically modified or labeled variants based on nucleotide molecules. Nucleotides are biomolecules consisting of a five-carbon sugar (deoxyribose or ribose), a nitrogenous base (cytosine (C), adenine (A), guanine (G), uracil (U), or thymine (T)), and a phosphate unit. Nucleotide derivatives are biologically active compounds, often used as raw materials for synthetic drugs, and some of them can be used directly as drugs, which has a variety of biological functions, such as participating in energy metabolism, protein biosynthesis, signal transduction and regulation of enzyme activity, etc. Therefore, the significance of derivatives is to expand the functions and effects, provide study tools and technical means, and thus promote the progress of scientific study, molecular diagnosis and treatment, drug development, and gene editing.

Nucleotide Derivative Production Services at CD BioGlyco

• Custom Synthesis Services

CD BioGlyco provides custom synthesis of nucleotide derivatives to meet the special requirements of research, including derivatives with specific sequences, lengths, or structures.

• Modification Services

CD BioGlyco provides nucleotide derivatives modification services, which can increase stability, change hydrophilicity/hydrophobicity, and can also endow nucleotides with new properties or functions by introducing other chemical groups. For example, phosphodiester modification, substrate-specific modification, etc.

• Labeling Services

CD BioGlyco provides nucleotide labeling services. For example, fluorescent labeling, radioactive labeling, biotin labeling, etc., to facilitate subsequent detection, imaging, and analysis.

• Purification Analysis Services

CD BioGlyco uses high-performance liquid chromatography, mass spectrometry, and other technologies to provide purification and purity analysis of nucleotide derivatives to ensure high-quality products.

• Large-scale Production Service

CD BioGlyco provides large-scale nucleotide derivative production services to ensure product consistency and stability.

Fig.1 Multiple types of nucleotide derivative production services. (CD BioGlyco)

CD BioGlyco provides a complete one-stop service including adenine, guanine, cytosine, uracil, and thymine nucleotides according to the research needs of clients.

Applications

• Molecular imaging: Labeled nucleotide derivatives can be used in molecular imaging to visualize and track specific nucleic acid sequences, which can be applied as a technology in fields such as biomedical, drug evaluation, and clinical diagnosis.
• Diagnosis and detection: Specific nucleic acid probes can be designed and synthesized to detect pathogens and mutation sites, which can be utilized in medical diagnosis, disease screening, and criminal identification.
• Gene expression: Precise gene editing and regulation can be achieved by modifying nucleotides, and promoting gene delivery and expression.
• Drug development: The stability and pharmacokinetic characteristics of derivatives are changed by modifying nucleotides, which can be applied in drug study and screening.

Highlights

• Custom synthesis: Custom synthesized nucleotide derivatives can be provided according to the client's needs.
• Fast delivery: CD BioGlyco efficiently designs and synthesizes desired nucleotide derivatives with fast delivery times.
• Diversity and flexibility: CD BioGlyco covers a wide range of nucleotide derivative types and modification methods. Clients choose the appropriate type according to their research needs.

CD BioGlyco provides a wide range of nucleotide derivatives production services. In addition, other Nucleotide-based Production Services are also provided. Please feel free to contact us for detailed information if you need to acquire our nucleotide derivatives service.