Guanine Nucleotide Derivative Production Service

Characterization of Guanine Nucleotide Derivative

Guanine nucleotide derivatives in general are composed of three parts, which are the phosphate group, pentose sugar, and guanine base. On the other hand, guanine nucleotide derivatives are also biological agents that have important physiological functions. For example, guanine nucleotide derivatives can modulate some of the antagonistic reactions and also participate in some of the metabolism as well as protein breakdown and synthesis. In addition, guanine nucleotide derivatives can be used in the field of chemical biopharmaceuticals and can increase the composition of drugs. Due to the characteristics of guanine nucleotide derivatives in terms of cell structure, metabolism, energy, and regulatory functions, a comprehensive study of its production is necessary.

Structural distribution of nucleotide composition.Fig.1 Structural distribution of nucleotide composition. (Wikipedia)

Guanine Nucleotide Derivative Production Service at CD BioGlyco

Guanine nucleotide derivatives have a high status in medicine. At CD BioGlyco, we offer services in the production of guanine nucleotide derivatives. We offer our clients both biological and Chemical Routes for the production of guanosine derivatives.

  • Biosynthesis is primarily catalyzed by the use of enzymes. The route is simple and does not require the protection of specific groups. On the other hand, the enzyme-catalyzed reaction conditions are extremely mild and produce higher yields of guanylate derivatives.
  • Chemical synthesis is one of the more comprehensive research methods. We will introduce specific functional groups to the molecule to change its structure and function. The guanosine monophosphate (GMP), Guanosine Cyclic Diphosphate (cGMP), Guanosine Diphosphate (GDP), and Guanosine Triphosphate (GTP) that we generate by phosphorylation of guanosine monophosphate (GMP) have already been used in a variety of biochemical processes.

Production is in the services of guanine nucleotide.Fig.2 Production is in the services of guanine nucleotide. (CD BioGlyco)

Applications

  • In biomedicine, guanine nucleotide derivatives are used in the study of immunomodulation in the human body.
  • In the pharmaceutical field, guanine nucleotide derivatives are used in research for the production of anti-inflammatory drugs.
  • Guanine nucleotide derivatives are used in research for the treatment of respiratory diseases in children.

Advantages

  • We have a professional research team and rich experience in the research of guanine nucleotide derivatives.
  • We have various routes in the production of guanine nucleotide derivatives to provide custom production solutions to our clients.
  • Our production follows stringent quality tests to ensure that the guanine nucleotide derivatives produced are of high purity.

CD BioGlyco has many years of experience in the production of guanosine acids. We fully combine chemical synthesis with biological synthesis to provide custom guanine nucleotide derivatives production services. Clients can contact our staff directly and we will respond promptly. If you are interested in our services, please feel free to contact us for more details.

Reference

  1. Schutter, C.D.; et al. Metabolism of nucleosides and nucleotides prodrugs. Current Pharmaceutical Design. 2017, 23(45): 6984-7002.
This service is for Research Use Only, not intended for any clinical use.

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