Cytosine Nucleotide Derivative Production Service

Applications of Cytosine Nucleotide Derivatives

Cytosine can usually combine with ribose molecules to form cytidine, which is involved in the synthesis of nucleic acids and serves as a precursor for the production of nucleotides containing cytosine. Cytosine nucleotide is a nucleotide containing cytosine base, one of the building blocks of DNA and RNA. Derivatives can be formed by introducing different chemical modifications, labels, or other functional units on cytosine nucleotide molecules, which can change their properties, increase specific functions, or regulate reaction characteristics. The preparation and application of these derivatives can be used in molecular biology, drug development, molecular diagnosis, biosensors, and other fields. They can serve as experimental tools and drug candidates, helping researchers gain insight into biological processes such as cell signaling, gene expression regulation, and disease mechanisms. Cytosine nucleotide derivatives can also be introduced into polypeptides, proteins, or other polymers to form new functional materials.

One-stop Cytosine Nucleotide Derivative Production Services at CD BioGlyco

  • Custom Synthesis Services

CD BioGlyco synthesizes cytosine nucleotide derivatives with specific chemical modifications or functions according to the client's needs.

  • Chemical Modification and Functionalization Services

CD BioGlyco introduces specific chemical modifications or functional units on cytosine nucleotide derivative molecules to change their properties and functions. For example, phosphate modification, glycosyl modification, amino ester modification, etc.

  • Polypeptide or Protein Modification Services

CD BioGlyco introduces cytosine nucleotide derivatives into polypeptides, proteins, or other polymers to regulate their functions and properties.

  • Labeling and Probe Preparation Services

CD BioGlyco provides label introduction services, and labels cytosine nucleotide derivatives as fluorescent dyes, radioactive isotopes, or other labels, which can be used in molecular biology research, cell imaging and analysis, and other fields.

  • Purification and Analysis Services

CD BioGlyco purifies and analyzes the synthesized cytosine nucleotide derivatives to ensure the purity and quality of the product, including reversed-phase high-performance liquid chromatography, mass spectrometry, and nuclear magnetic resonance.

  • Featured Products
    • Cytidine
    • Cytidine triphosphate (CTP)
    • Cytidine Monophosphate (CMP)
    • Cytidine analogs
    • 5-Methylcytosine nucleotide
    • 5-Hydroxymethylcytosine nucleotide
    • 5-Formyl cytosine nucleotide
    • 5-Carboxyl cytosine nucleotide
    • 5-Methylcytosine antibodies

One-stop cytosine nucleotide derivative production services.Fig.1 One-stop cytosine nucleotide derivative production services. (CD BioGlyco)

Applications

  • Drug development: Cytosine nucleotide derivatives can optimize the activity, selectivity, and biological stability of candidate drugs, and help researchers develop more effective and safer drugs.
  • Genetic engineering: Customized cytosine nucleotide derivatives can realize precise DNA sequence design and modification so that the functional analysis and regulation of specific genes can be realized. In addition, derivatives can also be used to prepare RNA molecules, such as siRNA and miRNA, which can be used in gene silencing.
  • Biomedical research: Cytosine nucleotide derivatives can be used to synthesize specific nucleic acid markers for molecular diagnostics, and signal transduction research. By customizing derivatives, researchers obtain high-purity, high-quality markers for more accurate and reliable experimental results.

Advantages

  • Professional team: CD BioGlyco has an experienced professional team with professional knowledge and technology in the field of nucleotide derivatives that can provide customers with accurate technical guidance and solutions.
  • Strict quality control: Products follow strict quality control standards to ensure that the provided cytosine nucleotide derivatives meet relevant specifications and requirements.
  • Fast Delivery: The product of cytosine nucleotide derivatives has a fast production and delivery cycle.

CD BioGlyco provides a full range of technical support and consultation related to cytosine nucleotide derivatives, including experimental design, synthesis optimization, and application advice. Moreover, Other Nucleotide Derivative Production Services are also provided, including Adenine Nucleotide Derivative Production Service, Guanine Nucleotide Derivative Production Service, Uracil Nucleotide Derivative Production Service, and Thymine Nucleotide Derivative Production Service. Please feel free to contact us as soon as possible if you are interested in our production service.

References

  1. Rublack, N.; Müller, S. Synthesis of a bifunctional cytidine derivative and its conjugation to RNA for in vitro selection of a cytidine deaminase ribozyme. Beilstein Journal of Organic Chemistry. 2014, 10(1): 1906-1913.
  2. Li, C.Y.; et al. Cytidine-containing tails robustly enhance and prolong protein production of synthetic mRNA in cell and in vivo. Molecular Therapy-Nucleic Acids. 2022, 30: 300-310.
This service is for Research Use Only, not intended for any clinical use.

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