Cancer Cell TCA Cycle Analysis

Mitochondria are the center of cellular energy metabolism, and the tricarboxylic acid cycle that occurs in mitochondria is a common metabolic pathway in aerobic organisms. Glucose, fat, and amino acid catabolism will eventually enter the TCA cycle for oxidative energy supply. At the same time, the TCA cycle is also the hub of glucose, fat, and amino acid metabolism.

CD BioGlyco can provide a specific analysis of glucose metabolism in the whole process of the TCA cycle. Help customers understand in detail the role of the TCA cycle pathway in cancer metabolic reprogramming, analyze changes in the genome, changes in metabolites, changes in metabolic flux, and changes in protein expression and modification during metabolism, in order to find targeted TCA cycle new therapeutic strategies for the acid cycle pathway.

Fig. 1 Transporters, fuels, enzymes, and biochemical reactions driving the TCA cycle (Anderson NM, et al., 2018)

What We Do

Our Advantages

• We provide specialized TCA cycle glucose metabolism analysis to help customers gain insight into the important role the TCA cycle plays in metabolic reprogramming in cancer.
• We provide comprehensive TCA cycle analysis services ranging from genomics to proteomics to comprehensively capture changes in the TCA cycle during cancer progression.

CD BioGlyco provides multi-omics analysis for cancer cell TCA cycle, including genomics, proteomics, metabolomics, and metabolic fluxomics, to help customers gain a comprehensive understanding of cancer cell TCA cycle. Our experienced teams of scientists, researchers, and technicians provide fast turnaround, high-quality services at competitive prices for worldwide customers. Our customers have direct access to our staff and prompt feedback on their inquiries. If you are interested in our services, please contact us for more details.

Reference:

1. Anderson NM, et al. The emerging role and targetability of the TCA cycle in cancer metabolism. Protein Cell. 2018 Feb; 9 (2): 216-237.