Researchers at CD BioGlyco are committed to providing a wide range of polysaccharide modification methods, including polysaccharide derivatization, grafting, crosslinking, and blending to help our clients prepare modified polysaccharides with desirable physicochemical properties and bioactivities.
As new materials emerge to meet the rapid increase of bioapplications, polysaccharides have been comprehensively explored due to their unique properties such as biocompatibility, bioactivity, and degradability. However, the bioactivity of natural polysaccharides has not always been in the condition of satisfaction. The bioactivities of polysaccharides and their physicochemical properties are directly or indirectly restricted by their structure. Therefore, some methods to modify the structure of polysaccharides are the fundamental way to solve these problems.
Molecular modification of polysaccharides is a method of structurally modifying their molecules by physical, chemical, and biological means to obtain numerous structural types of derivatives. Molecular modifications can enhance the biological activity of natural polysaccharides or give rise to new activities of polysaccharides by changing their spatial structure, molecular weight, and the type, position, and number of substituents. This will allow better study of the structure-activity relationships and enrich the range of polysaccharide compounds, providing more options for screening biological activity or specific polysaccharide agents.
Fig.1 Major methods of molecular modification of polysaccharides. (Li, et al., 2016)
We focus on polysaccharide structure-activity relationships to provide theoretical guidance in the direction of polysaccharide modifications, thereby accelerating our customers' research progress in the design, research, and development of Polysaccharide-based Biodegradable Materials. Our services include but are not limited to:
With a novel technology and a dedicated team of scientists, CD BioGlyco offers a wide range of polysaccharide modification services, including polysaccharide derivatization, polysaccharide grafting, polysaccharide crosslinking, and polysaccharide blending. We promise to provide customized solutions to meet the unique requirements of each client.
If you are interested in our business, please feel free to contact us for more details.
Reference
