Sugar-based modifications of nucleotides are of great importance in cells, and they play a key role in maintaining the normal function of organisms and regulating gene expression. Sugar-based modifications regulate the structure and function of DNA and RNA by adding or changing the chemical groups of the sugar group on the sugar ring, such as phosphorylation and methylation. These modifications affect the stability, binding affinity, and signaling processes of nucleic acids, which have important effects on biological processes such as gene expression and protein synthesis. The sugar-based modification also regulates cell differentiation and specialization and affects stem cell self-renewal and directed differentiation. Sugar-based modifications of nucleotides are important in drug development and therapy. In addition, sugar ring modification can be used for targeted therapy against specific genes or pathological processes, such as RNA interference technology and CRISPR-Cas gene editing systems.
Fig.1 Representative nucleotides with modifications to the sugar moieties. (Ma, et al., 2016)
CD BioGlyco specializes in providing top-notch sugar-based modification services and customized solutions for your needs. Our sugar-based modification technologies cover a wide range of modification types, including methylation, phosphorylation, etc., as well as combinations of various sugar-based modifications. Our sugar-based modification services include but are not limited to:
As a professional nucleoside and nucleotide sugar-based halogenation modification service provider, CD BioGlyco hopes to provide clients with customized solutions to meet their research needs.
At CD BioGlyco, our team utilizes state-of-the-art technology and instrumentation for methylation modification of different types of sugar groups, ensuring an efficient and controlled modification process.
We utilize the professional Glyco™ Synthesis Platform to provide our clients with professional sugar-based ring modification services and the expertise needed to solve a wide range of problems.
CD BioGlyco is committed to providing professional sugar-based saturation modification services. We guarantee high-quality laboratory operations and perform comprehensive quality control.
CD BioGlyco focuses on innovation and the application of technology to provide our clients with the most reliable sugar-based hydroxylation or dehydroxylation modification services.
CD BioGlyco provides comprehensive glycosidic bond modification services and develops a detailed plan to ensure that the modification services meet their research and application processes.
CD BioGlyco is committed to providing superior, customized solutions to help you make breakthroughs in the field of Nucleoside & Nucleotide and Oligonucleotide Modification.
CD BioGlyco provides professional sugar-based modification services to help you make breakthroughs in the field of glycobiology and medicine. Please feel free to contact us if you need sugar-based modification services, and we look forward to providing you with excellent services to help you achieve success in your research and application projects.
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