Nanohydrogel is a hydrogel material with a nanoscale three-dimensional network structure, which combines the advantages of high specific surface area and quantum size effect of nanomaterials with high water content and biocompatibility of hydrogels. This unique structure gives nanohydrogel many excellent properties, such as high drug loading, sustained release performance, good biocompatibility, controllable degradation, etc. With the advanced GlycoNano™ Platform, CD BioGlyco uses advanced technology to provide clients with unparalleled Glycol Nanohydrogel Development Services to meet your diverse needs in scientific research, development, and production. The Technologies we commonly use for the development of glycol nanohydrogels include but are not limited to:
We use different technologies to provide clients with the following glycol nanohydrogel development services, including but not limited to:
Our team provides clients with high-quality, customized carbohydrate-based nanohydrogel production services. We use rigorous scientific methods to ensure the quality of hydrogels through refined processing of raw materials, diverse synthesis strategies, precise functional modification, and comprehensive characterization analysis. Our services are as follows:
To meet the needs of our clients to the greatest extent, we provide flexible and diverse services. Clients provide us with purified carbohydrates so that we directly prepare hydrogels. We also extract and purify carbohydrates from raw materials and finally prepare high-purity carbohydrate nanohydrogels. The customized service ensures that we provide the most optimized solution based on the specific requirements of our clients. We prepare nanohydrogels based on the following carbohydrates:
To meet clients' diverse needs for nanohydrogel performance, we use a variety of hydrogel synthesis technologies, such as free radical polymerization, ionic crosslinking, physical crosslinking, microemulsion polymerization, etc. We finely control reaction conditions such as temperature, pH value, monomer concentration, crosslinker dosage, etc. to prepare nanohydrogels with different network structures, porosities, and mechanical properties.
We use scanning electron microscopy (SEM), transmission electron microscopy (TEM), dynamic light scattering (DLS), Fourier-transform infrared spectroscopy (FTIR), nuclear magnetic resonance (NMR), and other technologies to characterize the prepared nanohydrogel. Through comprehensive analysis of the hydrogel's morphology, particle size distribution, chemical composition, thermal stability, etc., we ensure the structure and performance of the prepared nanohydrogel.
DOI: 10.3390/polym15234501
Journal: Polymers
Published: 2023
IF: 4.7
Results: The development of scaffolds for bone regeneration is crucial for the treatment of bone diseases or injuries. The authors developed an injectable hydrogel for bone regeneration based on the natural polymer dextran, and incorporated inorganic compounds β-tricalcium phosphate and nanohydroxyapatite into the hydrogel structure to enhance the mechanical properties of its 3D mesh. Attenuated total reflectance-FTIR (ATR-FTIR) and NMR were used to characterize, and its degradation rate, swelling ability, release and mechanical properties were evaluated. The results showed that the dextran-based hydrogel was successfully synthesized with the drug release curve of 50%~80%, good biocompatibility, and Young's modulus (200-300 kPa), and has the potential to be used in bone regeneration applications.
Fig.1 ATR-FTIR spectra of dextran-based hydrogel. (Alves, et al., 2023)
CD BioGlyco helps clients develop biocompatible, degradable, and modifiable carbohydrate-based nanohydrogels for drug delivery, tissue engineering, etc. Please feel free to contact us and we will tailor a solution for you.
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