Glycosylation Related Products

Glycosylation Related Products

Unleash the Power of Glycan with Our Glycosylation Products!

Glycosylation-related products are a range of biochemical tools used in a variety of bioengineering and pharmaceutical research. They are used to study and manipulate an important post-transcriptional modification called glycosylation, in which glycan molecules attach to proteins and enable them to function properly. These products involve glycosylation enzymes, glycosylation substrates, glycan chain analysis reagents, which are of great significance for in-depth research on the glycosylation process and revealing its regulatory mechanism in life activities.

At CD BioGlyco, we provide a full range of glycosylation-related products designed to support a wide range of research and diverse applications. We provide cell surface modification, glycoprotein purification, glycan labeling and analysis, control proteins, deglycosylation, glycoprotein detection, and other glycosylation-related products for various applications. In addition, we also offer glycosylation-related products such as inhibitors and substrates, glycan components, and glycan-binding proteins. Each product guarantees reliability and high-quality performance, allowing experts to effectively facilitate experiments related to cell communication, molecular stability, and immune responses.

Categories of glycosylation-related products. (CD BioGlyco)

In the field of cell surface modification, glycosylation plays a crucial role. The cell surface modification-related glycosylation products we provide are designed to help researchers precisely regulate the glycan chain structure on the cell surface, thereby enabling in-depth exploration of cell function, signal transduction, and immune response. These products are not only highly specific and active but also easy to operate, providing powerful tools for researchers in the fields of cell biology and drug discovery. The following table shows some related representative products.

Cat. No. Product Name
XGB776 FSL-biotin
XGB777 FSL-Fluorescein
XGB778 FSL-GB3
XGB779 FSL-LEa(tri)
XGB780 FSL-A(tri)
XGB781 FSL-B(tri)
XGB782 FSL-Tyr1

Glycoprotein purification is an integral part of glycosylation research. We provide a series of efficient glycoprotein purification products designed to help researchers quickly and accurately isolate target glycoproteins from complex biological samples. These products combine advanced separation technology and highly selective identification capabilities to ensure high efficiency and purity of the purification process, laying a solid foundation for subsequent glycosylation analysis and functional research. The following table shows some related representative products.

Labeling and analysis of glycan chains are key steps in glycomics research. We provide a variety of glycan chain labeling and analysis products, aiming to help researchers achieve precise analysis and quantitative determination of glycan chain structures. These products have high sensitivity and high resolution and can reveal subtle differences and dynamic changes in glycan chains, providing strong support for glycobiology research. The following table shows some related representative products.

In glycosylation studies, control proteins are an important tool to verify the accuracy and reliability of experiments. The control protein products we provide undergo strict quality control to ensure that they are highly similar in structure and function to the target glycoprotein. These control proteins can be used to establish experimental standard curves, evaluate the specificity and sensitivity of experimental methods, and serve as negative or positive controls to provide researchers with a reliable experimental basis. The following table shows some related representative products.

The regulation of glycosylation reactions is of great significance for drug development and biological research. We provide a series of highly effective glycosylation inhibitors and substrate products, aiming to help researchers precisely regulate the glycosylation process and explore its key role in life activities. These products are highly specific and active, can achieve selective inhibition or activation of glycosylase, and provide a powerful tool for revealing the regulatory mechanism of glycosylation. The following table shows some related representative products.

Glycan chains are complex structures composed of different types of glycan groups. We provide a variety of glycan-based component products, including monosaccharides, oligosaccharides, and polysaccharides. These products have a high degree of purity and structural stability and are suitable for many aspects such as glycan chain synthesis, structural analysis, and functional research. Researchers can select appropriate glycosyl components as needed and construct specific glycan chain structures to explore the specific role of glycosylation in biological processes. The following table shows some related representative products.

O-glycan chain is an important glycan chain structure in the glycosylation process and is widely present in glycoproteins and mucopolysaccharides on the cell surface. We provide a variety of O-glycan products, which not only help researchers gain an in-depth understanding of the biosynthesis and regulatory mechanisms of O-glycans but also provide strong support for drug research and development.

N-glycans are another important glycan chain structure, mainly connected to the asparagine residues of proteins. We provide a variety of N-glycan products, which help researchers reveal the key role of N-glycans in protein folding, stability and cell signaling, and provide new ideas for drug design.

Glycosphingolipids are a class of sphingosine-containing glycolipid compounds that play an important role in the composition and function of cell membranes. We provide a variety of glycosphingolipid products that help researchers gain a deeper understanding of the role of glycosphingolipids in cell signaling, cell adhesion, and migration.

Glycosaminoglycans and proteoglycans are important components of the extracellular matrix and regulate cell growth, differentiation, and tissue function. We offer a variety of glycosaminoglycan and proteoglycan products that help researchers uncover the interactions of glycosaminoglycans and proteoglycans in the extracellular matrix.

Deglycosylation is an important technique in glycosylation research, helping to reveal the essential properties and functions of glycoproteins. We provide efficient and specific deglycosylation products that can quickly remove glycan chains on glycoproteins to expose hidden protein structures or sites. These products provide researchers with powerful tools to deeply understand the structure and function of glycoproteins, helping to advance the fields of glycobiology and drug discovery. The following table shows some related representative products.

The detection of glycoproteins is the basis of glycosylation research. We provide a series of highly sensitive glycoprotein detection products, including antibodies, probes kits, etc., which can achieve rapid and accurate detection of glycoproteins. Whether used for disease diagnosis, drug screening, or basic research, our glycoprotein detection products can provide researchers with reliable data support. The following table shows some related representative products.

The interaction between glycan chains and proteins plays a key role in living organisms. The glycan chain-binding protein products we provide can specifically recognize and bind specific glycan chain structures, providing researchers with a powerful tool to reveal the interaction mechanism between glycan chains and proteins. These products can not only be used in basic research but can also be applied in areas such as drug design and disease treatment, injecting new vitality into the development of glycobiology. The following table shows some related representative products.

Publication Data

Journal: Cells

IF: 6.0

Published: 2023

Results: The authors had developed a customizable flux-conditioned FC-E8 medium that permitted stem cell cultivation with stable isotopes for metabolic tracking, alongside a specific liquid chromatography-mass spectrometry (LC-MS/MS) technique that focused on metabolic pathways integrating in nucleotide sugar biosynthesis. Through the utilization of 13C6-glucose supplementation, they were able to track carbon integration into nucleotide sugars over time, both directly via glucose and indirectly through alternate pathways like glycolysis and pentose phosphate pathways, within induced pluripotent stem cells and embryonic stem cells.

Fig.1 Schematic representation of the NS biosynthesis.Fig.1 Schematic representation of the nucleotide sugar biosynthesis as metabolic link between glucose and glycosylation. (Conte, et al, 2023)

Applications of Glycosylation Related Products

  • Glycosylation-related products are widely used in biochemical research to analyze the structure and function of glycosylated proteins. By using specific glycosylases and substrates, researchers simulate or regulate the glycosylation process of proteins to explore the impact of glycan chains on protein stability, folding, and biological activity.
  • Glycosylation-related products provide powerful tools for glycosylation modification of drugs. By regulating the degree and type of glycosylation of drugs, researchers improve the solubility, stability, and bioavailability of drugs.
  • Using glycosylation-related products, researchers regulate the structure and density of glycan chains on the cell surface and then explore the specific impact of glycosylation modifications on cell behavior.

Advantages of Us

  • We have rich experience and professional knowledge and launch innovative glycosylation-related products to meet the diverse needs of scientific research.
  • Our research and development team continues to explore new glycosylation technologies and methods and is committed to providing clients with higher-quality and more reliable products.
  • We value each client's unique needs and are committed to providing personalized solutions.

Frequently Asked Questions

What is the quality of your company's glycosylation related products?

Our company strictly controls the quality of glycosylation related products. We use advanced processes and purification technologies to ensure that our products have the required purity and activity.

Does your company provide technical support?

Our company provides comprehensive technical support to ensure that you can receive timely responses and guidance when consulting on glycosylation-related products. Our technical support team is composed of experienced professionals with a deep background in biochemistry and glycosylation research, who can provide you with professional product usage suggestions and data analysis support.

As a professional company in the glycan field, CD BioGlyco continuously launches new glycosylation products to meet diversified needs. We always adhere to client demand and are committed to providing clients with high-quality and efficient products to facilitate research in the field of glycosylation. Please feel free to contact us if you have customization needs or other questions.

Reference

  1. Conte, F.; et al. Isotopic tracing of nucleotide sugar metabolism in human pluripotent stem cells. Cells. 2023, 12(13): 1765.

Christmas 2024

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